Scottsburg is a historic railroad depot located at Scottsburg, Scott County, Indiana. It was built in 1872 by the Jeffersonville, Madison and Indianapolis Railroad, costing almost $1,492. It is a one-story, Stick Style frame building with board and batten siding and a projecting agent's window. Its presence influenced the location of Scottsburg in 1874, as the town was named for the railroad's General Superintendent, Horace Scott. It was built specifically for both passenger and freight cargo. Inside there was separate waiting rooms for men and women. Passenger service to the station ended in the 1950s. It is one of the last structures of its kind still standing in Indiana.